Observation: This is Mary's interaction with the angel Gabriel, announcing the good news about her bearing God's only son. She asks an important question; "How can this happen?"
Application: Having recently asked that question concerning the news of my wife being pregnant with Reuben, I can relate to the panic, the fear, the joy. When I announced it to our church's leadership I even made the comment "How did this happen (joyfully surprised) and one of our leaders said, pastor, you know very well how this happened!" LOL
This story and question remind me that God's wisdom is very different than our own. As it was for Mary, so it is for us. The impossible things for us are always possible for God.
That is the beauty of Xmas!
Prayer: Lord thanks for making the impossible possible. You provide gifts for us that we may not understand!